Drugs that decrease effects of indinavir 1 didanosine didanosine increases gastric ph and decreases absorption of indi- navir.
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administration of indinavir with a high-fat meal markedly reduces the rate and extent by approximately 35 to 75 of drug absorption; however, food has little effect on indinavir pharmacokinetics when the drug is administered with a low dose of ritonavir.
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the effects of coadministration of crixivan on the auc, cmax and cmin are summarized in table 2 effect of other drugs on indinavir and table 3 effect of indinavir on other drugs .
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target hiv protease indinavir mk-639 is a protease inhibitor used as a component of highly active antiretroviral therapy haart to treat hiv infection and aids.
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clotrimazol, fluconazol, fluoxetina, fluvoxamina, metronidazol, nefazodona, saquinavir, o zileuton porque los efectos secundarios de cafergot pueden ser aumentados antif ngicos de azol por ejemplo, itraconazol, ketoconazol, voriconazol , beta-bloqueadores por ejemplo, propranolol , delavirdina, inhibidores de proteasa de vih por ejemplo, delavirdina, indinavir, nelfinavir, ritonavir , efavirenz, los antibi ticos ket lidos por ejemplo, telitromicina , antibi ticos macr lidos por ejemplo, eritromicina, claritromicina , o agonistas selectivos de 5-ht por ejemplo, sumatript n, eletript n , porque el riesgo de efectos secundarios graves, incluyendo latidos irregulares o disminuci n de ox geno a las extremidades por ejemplo, manos, pies o en el cerebro, puede ser aumentado agentes presoras por ejemplo, norepinefrina o simpaticomim ticos por ejemplo, pseudoefedrina, albuterol , porque el riesgo de efectos secundarios, incluyendo la presi n arterial muy alta, puede ser aumentado quinolonas por ejemplo, levofloxacina , porque el riesgo de efectos secundarios, tales como nerviosismo, insomnio, latidos cardiacos r pidos, puede ser aumentado teofilina porque las acciones y los efectos secundarios pueden ser aumentados por cafergot.
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